This conference is held every two years and focuses on topics related to human brain research. The brain, which is at the centre of all our behaviours, actions and emotions, is unfortunately also subject to numerous pathological conditions. The theme of the 2023 edition will focus on innovations in neurotechnology under the title ‘Fiction or Reality’ and how these will impact the lives of patients in the very near future. The conference programme is developed by the FESN scientific committee chaired by Prof. Pierre Magistretti and organised with the support of Magnoglia, a Monegasque company specialising in the research and development of innovative pharmaceutical products in this field.